A defined protocol.
Measured results.
Test. Restore. Re-test. Precision-matched FMT for licensed practitioners: a defined four-bottle Microbiome Restoration Protocol, guided by precision testing. Each patient’s baseline deep sequencing is matched to a donor using our proprietary donor matching algorithm, and product is manufactured on demand for that named patient under a Health Canada Drug Establishment Licence.
Not just any donor. A matched donor.
Conventional FMT treats every patient the same way. Novel Biome starts with the patient’s own microbiome and matches the donor to it.
One size fits all.
Any screened donor, any patient. The donor is chosen without looking at the patient’s own microbiome.
The donor is matched to the patient.
Each patient’s baseline deep sequencing is matched to a donor using our proprietary donor matching algorithm, built on current microbiome science, which improves as more patients are treated. Designed for the best possible match, aiming for the best possible outcomes. [Foley Hoag: review “proprietary algorithm that improves as more patients are treated”]
Donor matching is part of how product is selected for each patient. It is not a diagnosis and does not predict an individual result. Clinical decisions remain with the treating practitioner.
Two doors in.
Practitioners qualify for an account to see protocol materials, specifications and pricing. Patients and caregivers learn how microbiome restoration works and how to access it through a licensed practitioner.
Bring microbiome restoration into your practice.
- The four-bottle Microbiome Restoration Protocol
- Baseline and follow-up sequencing through CM Bio
- Donor matching from your patient’s baseline test
- An onboarding call with Sarah, then your account
- Webinars, office hours and patient handouts
Understand dysbiosis and your options.
- What dysbiosis and microbiome restoration mean
- How access works through a licensed practitioner
- Questions to bring to your practitioner
One underlying imbalance. One defined approach.
Dysbiosis describes a disruption in the balance of the gut microbial community. Instead of separate approaches for each condition, Novel Biome is organized around a single, standardized Microbiome Restoration Protocol that practitioners can apply consistently and measure the same way every time.
[Greg: regulatory definition of dysbiosis, state vs condition, before publishing]
Consistent by design
One protocol, the same steps for every case, with the donor matched to each patient. Simpler to implement in a busy practice and easier to explain to patients.
Measured, not assumed
Deep shotgun metagenomic sequencing at baseline and follow-up gives you an objective view of the microbiome before and after the course.
Comparable across clinics
Standardized steps produce standardized data, so cases can be documented and reviewed the same way across our practitioner network.
Test. Restore. Re-test.
Every Microbiome Restoration Protocol is bracketed by deep genome sequencing. The baseline result is also used to match your patient to a donor, so you start with data, match with data and finish with data.
Test
Your patient completes a CM Bio stool test using deep shotgun metagenomic sequencing. You receive the report before the protocol begins.
CM Bio sequencingMatch
Our proprietary donor matching algorithm matches your patient’s baseline profile to a donor from our screened donor pool.
Precision-matchedRestore
After recommended pre-treatment, three months of the four-bottle Microbiome Restoration Protocol, manufactured on demand for your named patient from the matched donor and shipped cold chain with handling instructions.
4 bottlesRe-test
A follow-up CM Bio test one month after FMT ends shows how the microbiome has changed, documented alongside your own clinical assessment.
CM Bio sequencingHow every lot is made and released.
Donor selection, testing, quarantine and release follow written procedures under our Health Canada Drug Establishment Licence. Full parameters are provided to registered practitioners.
Donor assessment
Medical history, lifestyle and medication review against written exclusion criteria.
Laboratory screening
Stool screening first, then blood and urine panels, on a defined schedule.
Quarantine
Material is held until the applicable testing cycle is complete.
Release
Finished product is tested in-house and released against specification.
Learn the protocol with the people who built it.
Live webinars, recorded sessions and recurring office hours for registered practitioners. Bring a real case and talk it through with our team.
[TBC]
You will know who you are calling.
Partner support is not a ticket queue. The same small team handles onboarding, protocol questions and case discussions.
Jason Klop
Leads protocol design and case review for partner clinics. [verify: bio wording]
Shaina Cahill, Ph.D.
Oversees donor screening, research and quality systems.
Sarah Douglas, R.H.N.
Your first call. Sarah runs onboarding, account approval and ongoing support for every partner clinic.
Qualify
Tell us your role, licence and where you practise.
Onboarding call
A short call with Sarah on the protocol, sequencing, donor matching, ordering and patient handouts.
Approved account
Pricing, the Protocol Book, CM Bio test ordering, sub-accounts and education, in one place.
Two ways in.
Register if microbiome restoration belongs in your practice. Book a call if you want to talk it through first.
Clinical partner registration
Licence verification, onboarding call and account setup.
Register your clinic →
TALK FIRSTCall with our team
A 30-minute conversation about fit, the protocol and sequencing.
Book a call →